The Botanical Power for Aquatic Protection, Growth and
Health
Amphi-SPEAR aquaculture
A synergistic blend of natural essential oils designed to support aquatic
animal health and water quality; providing antimicrobial, immune
enhancing, growth promoting and stress-relieving effects for fish and
shrimp farms
Reference:
Utilizing Medicinal Plants for Disease
Treatment in Aquaculture: An Approach to
Improve Fish Health. M A R K H O R (THE
JOURNAL OF ZOOLOGY). Volume 5, Issue 3
(July-Sep 2024)
Role of medicinal plants in aquatic animal
health and disease treatment
Medicinal plants as natural and environmentally friendly ways to
enhance fish health and manage diseases
• Aquaculture is the farming of fish and aquatic plants as a crop that
contributes to meeting global needs for seafood while also presenting an
attractive alternative in response to overfishing.
• Botanicals were being used more and more in aquaculture to promote fish health
as well as for disease prevention. Similarly, some plants with well documented
broad-spectrum antimicrobial, immunomodulatory activity, and antioxidant
properties. These can be advantageous as supplements in fish feed to stimulate
the immune function of fish.
• Plant extracts may exert positive effects on animal health through different
modes rather than relying solely on a single mode. Using herbs as dietary
additives has been shown to enhance immunity defense mechanisms.
• Recently, botanical treatments have been incorporated into aquaculture,
resulting in increased growth rates and disease resistance, thus giving rise to
more sustainable practices.
• They can be incorporated with sustainable approaches, such as the aquaponics
system, and possibly remain organic accredited, all while decreasing chemical
residue on food products and sustaining environmental wellness. These emerging
botanical approaches promise environmentally sustainable strategies for disease
management in aquaculture, supporting the consumer shift to demand safe and
sustainably produced seafood.
• The advantages that botanical treatments offer indicate them as essential tools
for the development of a sustainable and eco-friendly aquaculture industry
Reference:
Utilizing Medicinal Plants for Disease Treatment in Aquaculture: An Approach to Improve Fish
Health. M A R K H O R (THE JOURNAL OF ZOOLOGY). Volume 5, Issue 3 (July-Sep 2024)
Plant-based techniques in aquaculture provide a unique and
sustainable way to improve fish health, improve productivity,
and reduce environmental impact
• Aquaculture, when combined with plant-based techniques, provides a
unique and sustainable way to improve fish health, improve productivity,
and reduce environmental impact. Research continues to show the
therapeutic potential of plants was effective in the removal of pollutants and
chemical stressors that clean up aquatic ecosystems, improving their
overall health. Whether in salmon farming in Europe, or tilapia farming in
Africa, these techniques continue to offer benefits such as increased
disease resistance, improved growth, and reduced reliance on antibiotics.
• Aquaculture practices incorporating plant-derived products were more
sustainable and resilient disease control strategies. As research expands
and practices that can support the profession evolve, phyto-therapy was
poised to reshape the future of aquaculture worldwide.
Reference:
Exploring the Roles of Dietary Herbal Essential Oils in Aquaculture: A Review. Animals 2022, 12, 823.
Roles of Dietary Herbal Essential Oils in
Aquaculture
Growth-promoting, antibacterial, and immuno-stimulant effects
of essential oils (aetheroleum) as well as analgesic, adaptogen,
and astringent properties for fish species
• Essential oils, also known as aetheroleum, have a variety of therapeutic
properties, including analgesic, adaptogen, and astringents, among others.
• Essential oils have potential growth-promoting, antibacterial, and immunostimulant effects for several fish species.
• Furthermore, they potentiate the anti-oxidative capacity and the resistance
of aquatic animals against infectious diseases.
Farming stressors and their impact on growth performance,
productivity, and mortality rates in aquaculture
• The aquaculture sector is one of the main activities contributing to food security
for humanity around the globe. However, aquatic animals are susceptible to
several farming stressors involved in deteriorated growth performance, reduced
productivity, and eventually high mortality rates.
• Intensive and super-intensive farming practices induce stress to the aquatic
animals, thereby increasing the possibility of infection with pathogenic invaders
Negative impacts of antibiotics and chemotherapies on aquatic
animals
• In some countries still, antibiotics and chemotherapies are comprehensively
applied to control biotic stressors. Aside from the apparent benefits, the
continuous usage of antibiotics develops bacterial resistance, deteriorates
bacterial populations, and accumulates these compounds in the aquatic
environment.
• Synthetic antibiotics and chemotherapies are commonly used to relieve the
negative impacts of infection, and enhance the immunological response and
overall well-being of aquatic animals. The continuous application of antibiotics
has resulted in several negative impacts on aquatic animals (e.g., bacterial
resistance developed against antibiotics, suppressed host immunity, imbalance of
microbial populations, and hazardous environmental features)
Reference:
Exploring the Roles of Dietary Herbal Essential Oils in Aquaculture: A Review. Animals 2022, 12, 823.
Importance of medicinal herbs and extracts, especially essential
oils, as environmentally friendly alternative additives
• Alternatively, environmentally friendly additives were used to avoid the direct
and indirect impacts on the aquatic ecosystem and human health. In aquaculture,
medicinal herbs and extracts are extensively used and approved for their growthpromoting, anti-inflammatory, and antioxidative properties.
• Herbal essential oils contain many bioactive components with powerful
antibacterial, antioxidative, and immunostimulant potentials, suggesting their
application for aquatic animals. Essential oils can be provided via diet and can
benefit aquatic animals by improving their well-being and health status.
• The use of essential oils in aquafeed has been studied in a variety of aquatic
animals to determine their beneficial roles and optimum doses. The outputs
illustrated that herbal essential oils are exciting alternatives to antibiotics with
prominent growth promotion, antioxidative, and immunostimulant roles.
Biological activities of EOs
Reference:
Chemistry, bioactivities, mode of action and industrial applications of essential oils. Trends in Food
Science & Technology. 18 April 2020
Reference:
Exploring the Roles of Dietary Herbal Essential Oils in Aquaculture: A Review. Animals 2022, 12, 823.
Actions and beneficial effects of herbal essential oils (EOs) on fish
health and performance
1. Medicinal herbs, also known as phytobiotics, and the essence and oil derivatives
of these plants, play significant roles as appetite enhancers, growth promoters,
and immuno-stimulators for aquatic animals.
2. Essential oils (EOs) have gained special focus as natural antioxidant and
immuno-stimulant agents.
3. The chemical structural compound of EOs is resistant to gastric acid, ensuring its
efficacy and effect.
4. Furthermore, these volatile oils enhance palatability and regulate appetite
control genes in the hypothalamic-pituitary glands of fish.
5. EOs show a strong antibacterial effect against pathogenic bacteria by impairing
their activity and damaging the bacterial cell walls. Then, beneficial bacteria play
influential roles in food digestion mediated by the secretion of digestive
enzymes, along with improved local intestinal immunity and high resistance to
the challenged pathogens.
6. In addition, EOs enhance the permeability of intestinal barriers and increase
intestinal nutrient absorption.
7. The immune system-boosting effects of EOs are attributed to the increase in
intestinal immunity. The balanced intestinal microbiota (increased abundance of
beneficial microorganisms and decreased abundance of pathogenic
microorganisms), the inhibition of pathogenic bacteria’s adhesion sites, and the
modification of the intestinal pH are the primary actions of EOs to relieve the
pathogenic effects of bacteria on aquatic animals. In fish challenged with
pathogenic bacteria, EOs have been shown to improve the survival rate of many
species.
8. Further, Eos contain high concentrations of polyphenols and natural
antioxidants that remove the free radicals that cause lipid peroxidation and
immune cell damage.
Actions and Benefits of Herbal Essential
Oils in Aquaculture
Reference:
Adapted from “Exploring the Roles of Dietary Herbal Essential Oils in Aquaculture: A Review”.
Animals 2022, 12, 823.
• Essential oils (EOs) are a lipophilic mixture of organic compounds from the
secondary metabolism of aromatic plants, which mostly are limpid liquid
(colorless) with an obvious fragrance.
Menthol (mint camphor)
• Primary component (70–90%) in peppermint (Mentha piperita) and cornmint
(Mentha arvensis) EOs. It promotes growth and has antimicrobial potential,
though specific aquaculture studies are limited in the review. Noted for its role in
EO blends for overall health enhancement, with potential to reduce stress and
improve feed palatability.
• Actions:
1. Promotes growth indices and feed utilization
2. Increases antioxidative capacity
3. Enhanced Immune response, anti-inflammatory, and pro-inflammatory related
genes
4. Increased resistance against chlorpyrifos toxicity
Carvacol
• Carvacol is a major phenolic monoterpenoid in oregano EO (Origanum vulgare). It
improves growth performance, feed efficiency, and gut health by modulating
microbiota (reducing pathogens like Vibrio spp. and promoting beneficial bacteria
like Propionibacterium). Antioxidant effects include elevated superoxide
dismutase (SOD) and catalase (CAT) levels. Immune benefits: increased lysozyme,
myeloperoxidase, and lymphocyte proliferation. Example: Encapsulated oregano
oil (7.5% carvacrol) boosted Nile tilapia growth by 15–20% and reduced oxidative
stress.
• Carvacrol exhibits a distinct set of biological activities including antioxidant,
antitumor, antibacterial, antifungal, and insecticidal properties
• Actions:
• Increased feed efficiency, lysozyme, total complement concentrations, and CAT
• Reduced MDA, total anaerobe counts, and Lactobacillus loads
Natural Sources of Essential Oils
Thymol (from Thyme Oil)
• Thymol is an isomer of carvacrol in thyme EO (Thymus vulgaris). It exhibits strong
antibacterial activity against Aeromonas hydrophila and enhances intestinal
morphology (e.g., villus height in rainbow trout). In blends, it synergizes with
carvacrol for better nutrient utilization and immunity (e.g., higher IgM levels).
Cineol/Eucalyptol (from Eucalyptus Oil)
• Main compound (up to 80%) in eucalyptus EO (Eucalyptus spp.). It contributes to
antimicrobial and antioxidant properties in multi-EO formulations. Present in
varying amounts in other plants (e.g., rosemary, tea tree). The review notes its
role in broad-spectrum pathogen control, though direct fish studies are emerging.
Reference:
Adapted from “Exploring the Roles of Dietary Herbal Essential Oils in Aquaculture: A Review”.
Animals 2022, 12, 823.
Pharmacological actions of rosemary oil as a phytogenic in
aquafeeds
• Rosemary, Rosmarinus officinalis, oil contains various active components such as
1,8-cineole, carnosol, carnosic acid, rosmarinicacid, β- and α- inene, camphor and
camphene. It has been used as a phytogenic in aquafeeds because of its
antiinflammatory, antimicrobial, anthelmintic, hepatoprotective and
antioxidant properties Reference:
The Efficacy of Rosemary Oil and Microencapsulated Essential Oils on Zeuxapta seriolae Mitigationin
Yellow tailKing fish, Seriola lalandi. Aquaculture Research. Volume 2025, Article ID 1609121, 9 pages
• Menthol (Peppermint
Oil) and Menthol Crystals
Important Essential Oils Used in Aquaculture
• Carvacrol (Oregano Oil)
and Thymol (Thyme Oil)
• Cineol (Eucalyptus Oil)
• Camphor (Rosemary Oil)
Reference:
Menthol essential oil is a practical choice for intensifying the production of Nile tilapia (Oreochromis
niloticus): Effects on the growth and health performances. j.aquaculture.2021.
Farming stressors and their effects on growth and health
performances
• Nile tilapia (Oreochromis tilapia) is originally grown in Africa and becomes one of
the leading farmed finish species globally for its reasonable nature as a candidate
for intensive systems.
• However, fish are expected to suffer from farming stressors devoted to intensive
conditions such as low dissolved oxygen, high levels of accumulated ammonia,
and low feed intake resulting in low growth and health performances. Therefore,
it must be considered to find practical strategies involved in sustaining the
productivity of tilapia reared in intensive systems.
1- Benefits of Menthol (Peppermint Oil)
and Menthol Crystals for Aquatic Animals
Nile tilapia (Oreochromis tilapia)
Menthol (Mentha arvensis)
Reference:
Menthol essential oil is a
practical choice for
intensifying the production of
Nile tilapia (Oreochromis
niloticus): Effects on the
growth and health
performances.
j.aquaculture.2021.
Menthol benefits and actions in aqua feed
• Several forms of medicinal herbs were incorporated in feeds, including powdered
or essential oils (EO) as feed or water supplements.
• Menthol is a naturally occurring monocyclic terpene found in the oil of the mint
tree, Mentha arvensis.
1. Menthol essential oil has many active pharmaceuticals such as menthone,
isomenthone, vitamin C, and monoterpene ketones that effectively enhance the
palatability of feed, immunity, and antioxidative responses.
2. Recently, the inclusion of menthol EO in Nile tilapia diets resulted in enhanced
growth performance and health status. Further, menthol EO activated the
immunity of fish to cope with the impacts of infectious, waterborne toxins, and
ammonia accumulation.
3. Menthol EO also has antioxidative capacity against oxidative stress induced by
unstable rearing conditions due to the abundant content of polyphenols and
natural antioxidative derivatives.
4. Besides, menthol EO is known for the content of attractive fragrances that have a
refreshment effect and can enhance the quality of fish's respiration and balance
in the rearing water.
5. Consequently, it can be hypothesized that including menthol EOs in Nile tilapia
diets could potentiate fish resistance against stressors and influences induced
by intensive farming conditions.
6. Under intensive conditions, dietary menthol EO increased the growth
performance and feed utilization of Nile tilapia. Further, Nile tilapia fed dietary
menthol EO in intensive conditions had well-regulated liver and kidney
functions with normal blood biochemical metabolite levels. Besides, dietary
menthol EO enhanced the antioxidative capacity in LD, MD, and HD conditions,
referring to high immune status and well-being.
Hazards of chemical agents used in aquaculture on health and
environment
• Antibiotics and chemical agents, including chlortetracycline, oxytetracycline, cotrimoxazole, sulphadiazine, sulphamethoxazole, and amoxicillin, are often
employed for the treatment of diseases in aquaculture. However, their extensive
use has led to issues, including potential environmental and health hazards.
• Among the many fish species cultivated for human consumption, Nile tilapia (O.
niloticus) is second to none in terms of output. Among its many admirable
qualities are its rapid expansion, low production costs, market demand, and
resilience in the face of extreme environmental stress.
• These traits make it an excellent choice for aquaculture systems that involve
intense and super-intensive practices. However, tilapia are subject to stress
factors like overcrowding, low dissolved oxygen, ammonia buildup, and poor
water quality when farmed intensively. Injury, disease transmission, and poor
health are more likely in such settings.
• This commercially essential species has an impressive tolerance to stress, but it
could benefit from techniques that increase its productivity and resistance to
infection.
Importance of herbal supplements and extracts as alternatives
• Studies have shown that herbal supplements and extracts enhance growth,
antioxidant defenses, and immune function in aquatic animals. Multiple studies
have highlighted the ability of herbal extracts to improve immune responses and
resilience against environmental stress.
Carvacrol and thymol benefits and actions in aqua feed
• Essential oils exhibit diverse biological functions owing to the natural volatile
molecules that plants create. The chemicals carvacrol and thymol, found in
abundance in oregano essential oil (OEO) produced from Origanum vulgare L.,
are recognized for their ability to promote development, fortify the
immunological status, reduce inflammation, and kill bacteria.
• Research has demonstrated that common carp (Cyprinus carpio), rainbow trout
(Oncorhynchus mykiss), and Nile tilapia (Oreochromis niloticus) benefit
economically and physiologically from including OEO in their diets. Reference:
The beneficial impact of oregano essential oil supplementation on growth, physiological function,
antioxidant activity, and immune response in Nile tilapia (Oreochromis niloticus) fingerlings under
Aeromonas hydrophila stress. Open Veterinary Journal, (2025), Vol. 15(3): 1424-1439
2- Benefits of Carvacrol (Oregano Oil) and
Thymol (Thyme Oil) for Aquatic Animals
Effect of oregano essential oil (OEO) on growth performance of
Nile tilapia (O. niloticus)
• Studies showed that Nile tilapia fed OEO supplemented diets experienced
substantial improvements in final body weight, feed intake, weight increase,
ADG, and final fish biomass.
Effect of oregano essential oil (OEO) on hematological
parameters of Nile tilapia (O. niloticus)
• Studies showed that Nile tilapia fed OEO supplemented diets experienced
markedly elevated levels of RBC, Hb, PCV, and MCV.
• The differential leukocyte count (WBCs) and lymphocytes significantly increased.
Effect of oregano essential oil (OEO) on Biochemical parameters
of Nile tilapia (O. niloticus)
• Oregano treatment significantly decreased AST and ALT levels.
• Albumin, total protein, and globulin levels increased dramatically.
• Oregano-fed fish had considerably lower creatinine levels.
Effect of oregano essential oil (OEO) on Immunological and
antioxidant parameters of Nile tilapia (O. niloticus)
• OEO fed tilapia fish showed a substantial improvement in immunological
indicators, such as phagocytic index, PA, and lysozyme activity.
• The antioxidant analysis demonstrated that oregano treatment markedly
elevated CAT, SOD, and GPx levels. Oregano fed animals had lower MDA activity,
indicating reduced lipid peroxidation.
Overall beneficial effects of oregano essential oil fed to Nile
tilapia (O. niloticus)
• Oreochromis niloticus fingerlings fed OEO had better growth rates, physiological
responses, and pathogen resistance; all of which are important in modern
intensive aquaculture.
• OEO, when incorporated in Nile tilapia diets, effectively reduces the stress
caused by Aeromonas hydrophila and improves immunological markers in fish
exposed to pathogens, making it a viable alternative to antibiotics.
• Because of the increased rate of growth, OEO should be added to fingerling Nile
tilapia diets.
Reference:
The beneficial impact of oregano essential oil supplementation on growth, physiological function,
antioxidant activity, and immune response in Nile tilapia (Oreochromis niloticus) fingerlings under
Aeromonas hydrophila stress. Open Veterinary Journal, (2025), Vol. 15(3): 1424-1439
Antiparasitic activities of thymol and carvacrol • Thymol and carvacrol represent 80% of the bioactive molecules identified in
oregano. They have a wide range of functional properties, including antiparasitic
activities in fish. Similar to oregano, thyme produces oil that is rich in thymol and
carvacrol as well as flavonoid aglycones and flavonoid glycosides.
• Thyme oil has been shown to have parasiticidal effect when tested in vitro and in
vivo in rainbow rout, Oncorhynchusmykiss, as treatment against Ichthyophthirius
multifiliis. There was a significant reduction (78%) in Sparicotyl echrysophrii
abundance in gilthead seabream, Sparusaurata, when treated with a
microencapsulated essential oil.
• The use of such additives by oral administration, either individually or
synergistically, has not yet been studied in YTK.
Reference:
The Efficacy of Rosemary Oil and Microencapsulated Essential Oils on Zeuxapta seriolae Mitigationin
Yellow tailKing fish, Seriola lalandi. Aquaculture Research. Volume 2025, Article ID 1609121, 9 pages
Medicinal plants as suitable alternatives to antibiotics • Medicinal plants are considered suitable alternatives to antibiotics because they
are cheap or profitable, ecological and natural, which is why they are extensively
used for aquaculture production
• Eucalyptus globulus is known to be one of the medicinal plants that could be
used as additives in animal feed
Actions of E. globulus and its value in aquaculture • E. globulus is cultivated globally due to its important characteristics. Some of
these characteristics include the ability of extracts from the leaves to serve as
antioxidants and antimicrobials as well as insecticides.
Nile tilapia (Oreochromis niloticus) as an important aquaculture
species and its role in global food security
• Nile tilapia (Oreochromis niloticus) is a good aquaculture species due to its ability
to tolerate low oxygen levels, strong fertility as well as fast growth. O. niloticus
has played a significant role in global food security
Effects of E. globulus on growth performance and feed utilization • The potential of aquaculture feeds is predicted using growth performance and
feed conversion ratio. The best growth performance and feed conversion ratio
was observed in fish fed diet supplemented with E. globulus. This implies E.
globulus in diets of O. niloticus could stimulate gut secretions hence improving
the synthesis of protein resulting in higher growth performance. Also, the best
growth performance recorded was the group fed E. globulus, which can also be
attributed to improved feed utilization. In addition, the best performance
observed in fish fed E. globulus could be a result of improved digestion and
absorption of feed due to stimulated secretion of protease in the intestine of O.
niloticus.
Reference:
EFFECTS OF EUCALYPTUS GLOBULUS LEAF EXTRACT ON GROWTH PERFORMANCE, FEED UTILIZATION
AND BLOOD BIOCHEMISTRY OF NILE TILAPIA (OREOCHROMIS NILOTICUS LINNAEUS, 1758).
Veterinaria Vol. 71, Issue 2. 2022
3- Benefits of Cineol (Eucalyptus Oil) for
Aquatic Animals
Effects of E. globulus on hematological parameters • A significant increase in white blood cells was observed in fish fed diet
supplemented with E. globulus. White blood cells play important roles in
nonspecific immune response since they play crucial role in cellular immunity as
well as disease response. Specifically, WBC protects fish and other organisms
from infections caused by chemical factors and microbes
• Also, fish fed E. globulus extract recorded higher values of red blood cells
Effects of E. globulus on blood biochemical properties
• Total protein (TP) has been used as an indicator of metabolism of protein and
innate immune function. Total protein (TP) increases as E. globulus extract
increased in diets.
Summary of beneficial effects of E. globulus administration in
Nile tilapia feed • E. globulus promotes growth performance, feed utilization and increases the
main hematological and biochemical parameters of O. niloticus fish.
Reference:
EFFECTS OF EUCALYPTUS GLOBULUS LEAF EXTRACT ON GROWTH PERFORMANCE, FEED UTILIZATION
AND BLOOD BIOCHEMISTRY OF NILE TILAPIA (OREOCHROMIS NILOTICUS LINNAEUS, 1758).
Veterinaria Vol. 71, Issue 2. 2022
E. globulus
4- Benefits of Camphor (Rosemary Oil)
for Aquatic Animals
The world tilapia aquaculture production and possible high
mortality and serious economic losses due to bacterial and
fungal infections
• In this era, the world capture fisheries alone can no longer sustain the need of
fish protein for the increasing world’s population. Due to its nature of rapid
growth, large size and palatability, tilapia is the focus of major aquaculture
efforts. The world tilapia aquaculture production doubled between 1986 and
1992, and this is followed by Chinese carps and salmonids in total
• farm production. Furthermore, tilapia is a good candidate for culture due to the
fact that it can tolerate, grow, and even reproduce in saline waters, although this
will not happen in a very high saline condition. The value of farmed tilapia has
also witnessed a great increase during the past two decades, going from US$ 154
million in 1984 to US$ 1800.7 million in 2002.
• However, diseases such as from bacteria and fungi that infect this species may
lead to mortality which causes serious economic losses.
• Under stress conditions (including poor water quality and high density of fish),
tilapia can easily be infected by several opportunistic pathogens belonging to
Streptococcus, Enterocuccus, Aeromonas, Pseudomonas, Vibrio, Flexibacter and
Edwarsiella.
Anti-fungal and anti-bacterial actions of camphor oil • Oil extract of camphor tree using different species of camphor has been proven in
experiment to have strong effects on the growth inhibition of fungi. As for
antibacterial, one of many chemical compound found in camphor oil which is
cinnamaldehyde, is very effective in inhibiting the growth of bacteria
• The addition of C. camphora with feed, showed significant effect in increasing the
immune response and resistance of tilapia against virulent bacteria, including A.
hydrophila. Reference:
Study on the antibacterial and antifungal effects of camphor oil; Cinnamomum camphora with
emphasis on the control of overpopulation of tilapia. International Journal of Fisheries and Aquatic
Studies 2015; 2(5): 337-340
INGREDIENTS
Each 1 liter contains:
• Carvacrol (Oregano Oil): 20 g
• Thymol (Thyme Oil): 10 g
• Menthol (Peppermint Oil): 30 g
• Menthol Crystals: 30 g
• Cineol (Eucalyptus Oil): 100 g
• Camphor (Rosemary Oil): 30 g
• Tween 80: 100 g
• Deionized Water: up to 1000 ml.
A synergistic blend of natural essential oils designed to support aquatic
animal health and water quality; providing antimicrobial, immune
enhancing, growth promoting and stress-relieving effects for fish and
shrimp farms
PRODUCT DESCRIPTION • Amphi-SPEAR aquaculture is a synergistic blend of natural essential oils designed
to support aquatic animal health and water quality; providing antimicrobial,
immune enhancing, growth promoting and stress-relieving effects for fish and
shrimp farms.
• Amphi-SPEAR aquaculture combines oregano, thyme, peppermint, eucalyptus,
rosemary oils, and menthol crystals, stabilized with Tween 80 for uniform
dispersion in water.
• Amphi-SPEAR aquaculture is characterized by being:
• 100% natural essential oil formulation.
• Broad-spectrum antimicrobial activity without antibiotic residues.
• Safe for continuous use in aquaculture systems.
• Easy dispersion in water due to Tween 80 stabilizer.
• Supports eco-friendly and sustainable aquaculture practices.
The Botanical Power for Aquatic Protection, Growth and
Health
Amphi-SPEAR aquaculture
A synergistic blend of natural essential oils designed to support aquatic
animal health and water quality; providing antimicrobial, immune
enhancing, growth promoting and stress-relieving effects for fish and
shrimp farms
PRODUCT BENEFITS
• Amphi-SPEAR aquaculture provides an antimicrobial action against
pathogenic bacteria, fungi, and protozoa in aquaculture systems.
• Amphi-SPEAR aquaculture enhances innate immunity and disease
resistance in fish and shrimp.
• Amphi-SPEAR aquaculture improves gill function and oxygen uptake in
fish owing to its inclusion of cineol and menthol.
• Amphi-SPEAR aquaculture helps reduce handling and environmental
stress due to the inclusion of camphor and peppermint oil.
• Amphi-SPEAR aquaculture helps growth promotion by improving feed
intake, digestion, and overall performance.
• Amphi-SPEAR aquaculture improves water quality by reducing microbial
load and biofilm formation in tanks and ponds.
The Botanical Power for Aquatic Protection, Growth and
Health
Amphi-SPEAR aquaculture
A synergistic blend of natural essential oils designed to support aquatic
animal health and water quality; providing antimicrobial, immune
enhancing, growth promoting and stress-relieving effects for fish and
shrimp farms
DIRECTIONS FOR USE
In water (pond/tank application):
• 100–150 mL per 1000 L of water, applied directly.
In feed (via top-dressing):
• 1–2 mL per kg of feed, mixed thoroughly before feeding.
Prophylactic use:
• Weekly application at maintenance dose to prevent disease outbreaks.
During disease challenge or stress:
• Double the recommended dose for 3–5 days.
N.B. Dosage may vary depending on species, age, stocking density, and
environmental conditions. Always consult a nutritionist or veterinarian
before use.
The Botanical Power for Aquatic Protection, Growth and
Health
Amphi-SPEAR aquaculture
Storage
• Store in a cool, dry place away from direct sunlight.
• Keep container tightly closed to prevent volatilization of oils.
• Shelf life: 24 months from date of manufacture under recommended
conditions.
• Keep out of reach of children and unauthorized personnel.
American Pharmaceutical Innovations Company®
The Botanical Power for Aquatic Protection, Growth and
Health
Amphi-SPEAR aquaculture
A synergistic blend of natural essential oils designed to support aquatic
animal health and water quality; providing antimicrobial, immune
enhancing, growth promoting and stress-relieving effects for fish and
shrimp farms
